BDBM50150687 CHEMBL410969::methyl 2-[(2S,3S)-2-[(2S)-2-{2-[(2S)-2-[(2S,3R)-3-(benzyloxy)-2-{2-[(2S,3S)-2-[(2S)-2-[(2S)-2-(2-{[(tert-butoxy)carbonyl]amino}-2-methylpropanamido)-3-methylbutanamido]-3-methylbutanamido]-3-methylpentanamido]-2-methylpropanamido}butanamido]-3-methylbutanamido]-2-methylpropanamido}-3-methylbutanamido]-3-methylpentanamido]-2-methylpropanoate
SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C(C)(C)NC(=O)OC(C)(C)C)C(C)C)C(C)C)C(=O)NC(C)(C)C(=O)N[C@@H]([C@@H](C)OCc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)NC(C)(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NC(C)(C)C(=O)OC
InChI Key InChIKey=PCHBJOLERCSJIL-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50150687
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Human)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair