BDBM50150953 CHEMBL3775209

SMILES CN(c1ccc(OCCCC(=O)NO)cc1)c1ncnc2ccccc12

InChI Key InChIKey=MGPSFMYVFDFUJS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50150953   

TargetHistone deacetylase 1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50150953(CHEMBL3775209)
Affinity DataIC50:  76nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50150953(CHEMBL3775209)
Affinity DataIC50:  2.46E+3nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50150953(CHEMBL3775209)
Affinity DataIC50:  34nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed