BDBM50155151 4-((1-methyl-1H-indol-3-yl)methylene)-3-(pyrazin-2-yl)-1H-pyrazol-5(4H)-one::4-(1-Methyl-1H-indol-3-ylmethylene)-5-pyrazin-2-yl-2,4-dihydro-pyrazol-3-one::CHEMBL364411

SMILES Cn1cc(\C=C2/C(=O)NN=C2c2cnccn2)c2ccccc12

InChI Key InChIKey=IVBFAQHEEUITPW-JYRVWZFOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155151   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155151(4-((1-methyl-1H-indol-3-yl)methylene)-3-(pyrazin-2...)
Affinity DataIC50:  230nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155151(4-((1-methyl-1H-indol-3-yl)methylene)-3-(pyrazin-2...)
Affinity DataIC50:  37nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155151(4-((1-methyl-1H-indol-3-yl)methylene)-3-(pyrazin-2...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT(dithiothreitol)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed