BDBM50155338 1-{4-[4-(4-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}butoxy)phenyl]but-3-yn-1-yl}-1-hydroxyurea::CHEMBL186125

SMILES NC(=O)N(O)CCC#Cc1ccc(OCCCCN2CCN(CC2)[C@H](c2ccccc2)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=MBQMCWRJVSGZMF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155338   

TargetHistamine H1 receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155338(1-{4-[4-(4-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]...)
Affinity DataKi:  30nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155338(1-{4-[4-(4-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]...)
Affinity DataIC50: 68nMAssay Description:Inhibition of 5-lipoxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed