BDBM50157248 5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)-methyl]-2''-methyl-biphenyl-2-carbonitrile::CHEMBL182978

SMILES Cc1ccccc1-c1cc(ccc1C#N)C(OCc1ccc(cc1)C#N)c1cncn1C

InChI Key InChIKey=LNNBTFQWNBDZFR-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50157248   

LigandPNGBDBM50157248(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Bovine farnesyl transeferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50157248(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataEC50:  420nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50157248(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Bovine farnesyl transeferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50157248(5-[(4-Cyano-benzyloxy)-(3-methyl-3H-imidazol-4-yl)...)
Affinity DataIC50:  180nMAssay Description:Inhibition of Bovine Geranyl geranyl transeferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed