BDBM50159363 CHEMBL177000::methyl 2-(2-{N-methyl-1-[(4R)-1-(naphthalene-2-sulfonyl)-4-sulfanylpyrrolidin-2-yl]formamido}acetamido)benzoate

SMILES COC(=O)c1ccccc1NC(=O)CN(C)C(=O)C1C[C@@H](S)CN1S(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=XQPOFONTMJXZRQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50159363   

TargetEndothelin-converting enzyme 1(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159363(methyl 2-(2-{N-methyl-1-[(4R)-1-(naphthalene-2-sul...)
Affinity DataIC50: 80.8nMAssay Description:Inhibitory concentration against human ECE-1 by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159363(methyl 2-(2-{N-methyl-1-[(4R)-1-(naphthalene-2-sul...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibitory concentration against human ECE-1 expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159363(methyl 2-(2-{N-methyl-1-[(4R)-1-(naphthalene-2-sul...)
Affinity DataIC50: 3.66E+4nMAssay Description:Inhibitory concentration against human angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159363(methyl 2-(2-{N-methyl-1-[(4R)-1-(naphthalene-2-sul...)
Affinity DataIC50: 8.19E+4nMAssay Description:Inhibitory concentration against NeprilysinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed