BDBM50161221 CHEMBL194493::N-{(E)-4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-4-nitro-benzamide::N-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-4-nitro-benzamide

SMILES [O-][N+](=O)c1ccc(cc1)C(=O)NC\C=C\CN1CCN(CC1)c1cccc(Cl)c1Cl

InChI Key InChIKey=DWDPBNBMFRTKEL-OWOJBTEDSA-N

Data  6 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50161221   

TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161221(CHEMBL194493 | N-{(E)-4-[4-(2,3-Dichloro-phenyl)-p...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of [125I]IABN binding to human Dopamine D3 receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161221(CHEMBL194493 | N-{(E)-4-[4-(2,3-Dichloro-phenyl)-p...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity for human dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161221(CHEMBL194493 | N-{(E)-4-[4-(2,3-Dichloro-phenyl)-p...)
Affinity DataKi:  3.5nMAssay Description:Inhibition of [3H]YM-09151-2 binding to human Dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161221(CHEMBL194493 | N-{(E)-4-[4-(2,3-Dichloro-phenyl)-p...)
Affinity DataKi:  19.7nMAssay Description:Inhibition of [125I]IABN binding to human Dopamine D2L receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161221(CHEMBL194493 | N-{(E)-4-[4-(2,3-Dichloro-phenyl)-p...)
Affinity DataKi:  19.7nMAssay Description:Binding affinity for human dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161221(CHEMBL194493 | N-{(E)-4-[4-(2,3-Dichloro-phenyl)-p...)
Affinity DataKi:  31nMAssay Description:Inhibition of [3H]YM-09151-2 binding to human Dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161221(CHEMBL194493 | N-{(E)-4-[4-(2,3-Dichloro-phenyl)-p...)
Affinity DataEC50:  13.8nMAssay Description:Inhibition of quinpirole stimulation of mitogenesis at human dopamine D2 receptors expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161221(CHEMBL194493 | N-{(E)-4-[4-(2,3-Dichloro-phenyl)-p...)
Affinity DataIC50:  2.20nMAssay Description:Mitogenic stimulation or antagonism of 30 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161221(CHEMBL194493 | N-{(E)-4-[4-(2,3-Dichloro-phenyl)-p...)
Affinity DataIC50:  13.8nMAssay Description:Mitogenic stimulation or antagonism of 30 nM quinpirole-stimulated mitogenesis in CHO cells expressing human dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50161221(CHEMBL194493 | N-{(E)-4-[4-(2,3-Dichloro-phenyl)-p...)
Affinity DataEC50:  2.20nMAssay Description:Inhibition of quinpirole stimulation of mitogenesis at human dopamine D3 receptors expressed in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed