BDBM50162160 1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-3-fluoro-phenyl]-urea::1-[4-(6,7-dimethoxy-quinolin-4-yloxy)-3-fluoro-phenyl]-3-(2,4-difluoro-phenyl)-urea::CHEMBL179815
SMILES COc1cc2nccc(Oc3ccc(NC(=O)Nc4ccc(F)cc4F)cc3F)c2cc1OC
InChI Key InChIKey=NZYLXYBIWNIAGH-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50162160
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Kirin Brewery
Curated by ChEMBL
Kirin Brewery
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of platelet-derived growth factor receptor alpha in cell-intact assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Hadassah Hebrew University Hospital
Curated by ChEMBL
Hadassah Hebrew University Hospital
Curated by ChEMBL
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of IGF1R by ELISAMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hadassah Hebrew University Hospital
Curated by ChEMBL
Hadassah Hebrew University Hospital
Curated by ChEMBL
Affinity DataIC50: >500nMAssay Description:Inhibition of Her2 expressed in CSH12 cells by western blot analysisMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University Hospital
Curated by ChEMBL
Hadassah Hebrew University Hospital
Curated by ChEMBL
Affinity DataIC50: >500nMAssay Description:Inhibition of EGFR expressed in DHER14 cells by western blot analysisMore data for this Ligand-Target Pair