BDBM50162777 CHEMBL180805::{2-[6-(2,2-Dimethyl-propoxy)-naphthalen-2-yl]-2-imidazol-1-yl-1-methyl-ethyl}-dimethyl-amine

SMILES CC(C(c1ccc2cc(OCC(C)(C)C)ccc2c1)n1ccnc1)N(C)C

InChI Key InChIKey=ZZGVWUSRXVYCSC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50162777   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162777(CHEMBL180805 | {2-[6-(2,2-Dimethyl-propoxy)-naphth...)
Affinity DataIC50:  700nMAssay Description:Selectivity towards cytochrome P450 3A4 enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162777(CHEMBL180805 | {2-[6-(2,2-Dimethyl-propoxy)-naphth...)
Affinity DataIC50:  21.4nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162777(CHEMBL180805 | {2-[6-(2,2-Dimethyl-propoxy)-naphth...)
Affinity DataIC50:  700nMAssay Description:Selectivity towards cytochrome P450 3A4 enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162777(CHEMBL180805 | {2-[6-(2,2-Dimethyl-propoxy)-naphth...)
Affinity DataIC50:  21.4nMAssay Description:Potency towards cytochrome P 450 26 enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed