BDBM50163313 CHEMBL3794179

SMILES Fc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1OC1CCOCC1)c1cc(F)ccc1F

InChI Key InChIKey=NMZBOFGYKWSRMA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50163313   

TargetPresenilin-1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163313(CHEMBL3794179)
Affinity DataIC50: 360nMAssay Description:Inhibition of human gamma-secretase expressed in CHO cells assessed as suppression of amyloid beta 40 production using C100-Flag as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163313(CHEMBL3794179)
Affinity DataIC50: 400nMAssay Description:Inhibition of human gamma-secretase expressed in CHO cells assessed as suppression of amyloid beta 42 production using C100-Flag as substrate incubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50163313(CHEMBL3794179)
Affinity DataIC50: 620nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as suppression of amyloid beta 42 production by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed