BDBM50165164 CHEMBL262135::CHEMBL430066::Radiolabeled octreotide derivative

SMILES C[C@@H](O)[C@H](NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2ccccc2)NC(=O)CN2CCN(CC([O-])=O)CCN(CC([O-])=O)CCN(CC([O-])=O)CC2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1)C(O)=O

InChI Key InChIKey=QVFLVLMYXXNJDT-UHFFFAOYSA-K

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50165164   

TargetSomatostatin receptor type 2(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165164(CHEMBL430066 | CHEMBL262135 | Radiolabeled octreot...)
Affinity DataIC50: 0.200nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 2 expressed in CCL39 cells; (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165164(CHEMBL430066 | CHEMBL262135 | Radiolabeled octreot...)
Affinity DataIC50: 1.60nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 2 expressed in CCL39 cells; (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165164(CHEMBL430066 | CHEMBL262135 | Radiolabeled octreot...)
Affinity DataIC50: 187nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 5 expressed in CHO-K1 cells; (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165164(CHEMBL430066 | CHEMBL262135 | Radiolabeled octreot...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 4 expressed in CCL39 cells; (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165164(CHEMBL430066 | CHEMBL262135 | Radiolabeled octreot...)
Affinity DataIC50: 377nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 5 expressed in CHO-K1 cells; (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165164(CHEMBL430066 | CHEMBL262135 | Radiolabeled octreot...)
Affinity DataIC50: 523nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 4 expressed in CCL39 cells; (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165164(CHEMBL430066 | CHEMBL262135 | Radiolabeled octreot...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 3 expressed in CCL39 cells; (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165164(CHEMBL430066 | CHEMBL262135 | Radiolabeled octreot...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 3 expressed in CCL39 cells; (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165164(CHEMBL430066 | CHEMBL262135 | Radiolabeled octreot...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 1 expressed in CHO-K1 cells; (n=4)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50165164(CHEMBL430066 | CHEMBL262135 | Radiolabeled octreot...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibition of [125I][Leu8,D-Trp22,Tyr25] somatostatin 28 binding to human somatostatin receptor type 1 expressed in CHO-K1 cells; (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed