BDBM50166718 (3S,4aR,6S,8R,8aR)-3-Furan-3-yl-4a,8a-dimethyl-1,5-dioxo-6-propoxy-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester::CHEMBL196670

SMILES CCCO[C@H]1C[C@@H](C(=O)OC)[C@]2(C)CCC3C(=O)O[C@@H](C[C@]3(C)C2C1=O)c1ccoc1

InChI Key InChIKey=RHHIHFNKCAJEAJ-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166718   

TargetKappa-type opioid receptor(Human)
Mclean Hospital

Curated by ChEMBL
LigandPNGBDBM50166718((3S,4aR,6S,8R,8aR)-3-Furan-3-yl-4a,8a-dimethyl-1,5...)
Affinity DataKi:  28.7nMAssay Description:Inhibition of [3H]diprenorphine binding to human Opioid receptor kappa 1 expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Mclean Hospital

Curated by ChEMBL
LigandPNGBDBM50166718((3S,4aR,6S,8R,8aR)-3-Furan-3-yl-4a,8a-dimethyl-1,5...)
Affinity DataEC50:  67.4nMAssay Description:Effective concentration for activation of human Opioid receptor kappa 1 expressed in chinese hamster ovary cells to enhance [35S]GTP-gamma-S, bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed