BDBM50168408 4-(5-Ethoxycarbamoyl-2,4-difluoro-phenylamino)-5-isopropyl-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid ethyl ester::CHEMBL195853

SMILES CCONC(=O)c1cc(Nc2ncnn3cc(C(=O)OCC)c(C(C)C)c23)c(F)cc1F

InChI Key InChIKey=IMJDWAAISYUCKT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50168408   

TargetVascular endothelial growth factor receptor 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50168408BDBM50168408(4-(5-Ethoxycarbamoyl-2,4-difluoro-phenylamino)-5-i...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human vascular endothelial growth factor receptor 2 (Flk-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed