BDBM50172024 2-Benzyl-4-(5-fluoro-2-hydroxy-phenyl)-2-hydroxy-4-methyl-pentanoic acid (1-oxo-1,3-dihydro-isobenzofuran-5-yl)-amide::CHEMBL196051

SMILES CC(C)(CC(O)(Cc1ccccc1)C(=O)Nc1ccc2C(=O)OCc2c1)c1cc(F)ccc1O

InChI Key InChIKey=KGFMFEQQZNKWLP-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50172024   

TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172024(2-Benzyl-4-(5-fluoro-2-hydroxy-phenyl)-2-hydroxy-4...)
Affinity DataIC50:  190nMAssay Description:Binding affinity towards mineralocorticoid receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172024(2-Benzyl-4-(5-fluoro-2-hydroxy-phenyl)-2-hydroxy-4...)
Affinity DataIC50:  60nMAssay Description:Binding affinity towards glucocorticoid receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172024(2-Benzyl-4-(5-fluoro-2-hydroxy-phenyl)-2-hydroxy-4...)
Affinity DataIC50:  35nMAssay Description:Binding affinity towards progesterone receptor using fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50172024(2-Benzyl-4-(5-fluoro-2-hydroxy-phenyl)-2-hydroxy-4...)
Affinity DataEC50:  420nMAssay Description:Effective concentration against inhibition of Dexamethasone induced glucocorticoid receptor transactivation of mouse mammary tumor virus luciferase g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed