BDBM50173254 CHEMBL434944::methyl 2-[1'-cyclooctylmethyl-2-oxospiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]acetate
SMILES COC(=O)CN1C(=O)C2(CCN(CC3CCCCCCC3)CC2)c2ccccc12
InChI Key InChIKey=HFUCMBMATFVNGH-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50173254
TargetDelta-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity against human opioid receptor delta 1 expressed in HEK293 cells using [3H]DDPDE radioligandMore data for this Ligand-Target Pair
TargetNociceptin receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Binding affinity determined by the ability to compete with [125I]-Tyr14- nociceptin from binding to human opiate receptor-like 1 expressed in HEK293 ...More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Binding affinity against human opioid receptor kappa 1 expressed in HEK293 cells using 3H-U69,593 radioligandMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 3.55E+3nMAssay Description:Binding affinity against human opioid receptor mu 1 expressed in HEK293 cells using [3H]DAMGO radioligandMore data for this Ligand-Target Pair