BDBM50173951 CHEMBL194984::N-[(3S)-1-azabicyclo[2.2.2]oct-3-yl]-5-phenylthiophene-2-carboxamide acetate

SMILES O=C(N[C@@H]1CN2CCC1CC2)c1ccc(s1)-c1ccccc1

InChI Key InChIKey=LEUSUHAAYXEGAO-OAHLLOKOSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173951   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173951(CHEMBL194984 | N-[(3S)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  26.9nMAssay Description:Binding affinity towards human nicotinic acetylcholine receptor alpha 7 expressed in GH4C1 cell using [3H]methyllycaconitineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50173951(CHEMBL194984 | N-[(3S)-1-azabicyclo[2.2.2]oct-3-yl...)
Affinity DataKi:  1.55E+3nMAssay Description:Binding affinity for human 5-hydroxytryptamine 3 serotonin membrane receptor using [3H]GR-65630More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed