BDBM50174378 1-(2-Chloro-4-fluoro-benzoyl)-3-(3,4-dihydroxy-phenyl)-urea::CHEMBL383387

SMILES Oc1ccc(NC(=O)NC(=O)c2ccc(F)cc2Cl)cc1O

InChI Key InChIKey=QDEMMBFTFIHBQE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174378   

TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50174378(1-(2-Chloro-4-fluoro-benzoyl)-3-(3,4-dihydroxy-phe...)
Affinity DataIC50:  120nMpH: 7.2Assay Description:Logarithmic inhibitory concentration against human liver glycogen phosphorylase enzyme by the addition of glucose-1-phosphate and incubated for 40 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, liver form(Homo sapiens (Human))
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50174378(1-(2-Chloro-4-fluoro-benzoyl)-3-(3,4-dihydroxy-phe...)
Affinity DataIC50:  120nMpH: 7.2Assay Description:Inhibitory concentration against human liver glycogen phosphorylase enzyme by the addition of glucose-1-phosphate upon incubating for 40 min at 25 de...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed