BDBM50174541 (3R,4S,5R,10R,13S)-10,13-Dimethyl-hexadecahydro-20-oxa-cyclopropa[3,4]cyclopenta[a]phenanthren-17-one::CHEMBL372334

SMILES C[C@]12CCC3C(CC[C@H]4[C@@H]5O[C@@H]5CC[C@]34C)C1CCC2=O

InChI Key InChIKey=ALHYGULCJHAJFX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174541   

TargetAromatase(Human)
University of Oporto

Curated by ChEMBL
LigandPNGBDBM50174541((3R,4S,5R,10R,13S)-10,13-Dimethyl-hexadecahydro-20...)
Affinity DataKi:  38nMAssay Description:Inhibition constant against aromatase protein from human placental microsomes using [1-beta-3H]-androstenedione; Competitive inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetAromatase(Human)
University of Oporto

Curated by ChEMBL
LigandPNGBDBM50174541((3R,4S,5R,10R,13S)-10,13-Dimethyl-hexadecahydro-20...)
Affinity DataIC50: 145nMAssay Description:Inhibitory concentration against aromatase protein from human placental microsomes using [1-beta-3H]-androstenedione; Competitive inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed