BDBM50177106 2-alpha-3-alpha-diphenyltropane::2-beta-3-beta-diphenyltropane::CHEMBL388850

SMILES CN1C2CCC1[C@H]([C@H](C2)c1ccccc1)c1ccccc1

InChI Key InChIKey=URXGPOFPBIBVGT-NBDWZHNGSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50177106   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177106(2-alpha-3-alpha-diphenyltropane | 2-beta-3-beta-di...)
Affinity DataKi:  550nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177106(2-alpha-3-alpha-diphenyltropane | 2-beta-3-beta-di...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177106(2-alpha-3-alpha-diphenyltropane | 2-beta-3-beta-di...)
Affinity DataIC50:  920nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177106(2-alpha-3-alpha-diphenyltropane | 2-beta-3-beta-di...)
Affinity DataIC50:  12.6nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177106(2-alpha-3-alpha-diphenyltropane | 2-beta-3-beta-di...)
Affinity DataIC50:  2.10E+4nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed