BDBM50178758 3,6-bis(Dmt-Tic-NH-butyl)-2(1H)-pyrazinone::CHEMBL373668

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)NCCCCc1[nH]c(=O)c(CCCCNC(=O)C2Cc3ccccc3CN2C(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)nc1C

InChI Key InChIKey=HHTSJHJHPFGARW-RFLUKDKXSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50178758   

TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178758(3,6-bis(Dmt-Tic-NH-butyl)-2(1H)-pyrazinone | CHEMB...)
Affinity DataKi:  0.323nMAssay Description:Displacement of [3H]deltorphin-II from delta opioid receptor in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178758(3,6-bis(Dmt-Tic-NH-butyl)-2(1H)-pyrazinone | CHEMB...)
Affinity DataKi:  1.74nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in rat brain synaptosomal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178758(3,6-bis(Dmt-Tic-NH-butyl)-2(1H)-pyrazinone | CHEMB...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonistic activity at mu opioid receptor in myenteric plexus longitudinal muscle of guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50178758(3,6-bis(Dmt-Tic-NH-butyl)-2(1H)-pyrazinone | CHEMB...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonistic activity at delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed