BDBM50179008 CHEMBL204813::sanggenon C
SMILES [#6]\[#6](-[#6])=[#6]/[#6][C@]12[#8]-c3cc(-[#8])c(-[#6@H]-4-[#6]=[#6](-[#6])-[#6]-[#6@@H](-[#6@H]-4-[#6](=O)-c4ccc(-[#8])cc4-[#8])-c4ccc(-[#8])cc4-[#8])c(-[#8])c3-[#6](=O)[C@@]1([#8])[#8]-c1cc(-[#8])ccc21
InChI Key InChIKey=XETHJOZXBVWLLM-HUKCQOFTSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50179008
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology (Kribb)
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology (Kribb)
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology (Kribb)
Curated by ChEMBL
Korea Research Institute Of Bioscience And Biotechnology (Kribb)
Curated by ChEMBL
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of VHR DS-PTPMore data for this Ligand-Target Pair
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of 6his/TEV-fused GST tagged SARS-CoV-2 MPro (1 to 306 residues) expressed in Escherichia coli RIL cells using 5-FAM-AVLQSGFR-Lys-(Dabcyl)...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Korean Research Institute Of Biosciences And Biotechnology
Curated by ChEMBL
Korean Research Institute Of Biosciences And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 8.26E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human Hep3B cells by pGL3-HRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
Korean Research Institute Of Biosciences And Biotechnology
Curated by ChEMBL
Korean Research Institute Of Biosciences And Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of hypoxia-induced HIF1alpha protein accumulation in human Hep3B cells treated for 30 mins measured after 12 hrs by Western blot analysisMore data for this Ligand-Target Pair