BDBM50180018 (S)-2,N*1*-Dihydroxy-3-isobutyl-N*4*-((S)-2-oxo-azacyclotridec-3-yl)-succinamide::CHEMBL200274

SMILES CC(C)CC([C@H](O)C(=O)NO)C(=O)N[C@H]1CCCCCCCCCCNC1=O

InChI Key InChIKey=JGRIYRSQHHLUHI-BSOSBYQFSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50180018   

TargetMatrilysin(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50180018((S)-2,N*1*-Dihydroxy-3-isobutyl-N*4*-((S)-2-oxo-az...)
Affinity DataIC50:  200nMAssay Description:Binding affinity to MMP7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50180018((S)-2,N*1*-Dihydroxy-3-isobutyl-N*4*-((S)-2-oxo-az...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50180018((S)-2,N*1*-Dihydroxy-3-isobutyl-N*4*-((S)-2-oxo-az...)
Affinity DataIC50:  20nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50180018((S)-2,N*1*-Dihydroxy-3-isobutyl-N*4*-((S)-2-oxo-az...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50180018((S)-2,N*1*-Dihydroxy-3-isobutyl-N*4*-((S)-2-oxo-az...)
Affinity DataIC50:  500nMAssay Description:Binding affinity to MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed