BDBM50180254 1-((S)-2-aminopropyl)-7-iodo-1H-indazol-6-ol::CHEMBL201132

SMILES C[C@H](N)Cn1ncc2ccc(O)c(I)c12

InChI Key InChIKey=NTWCUBZMEYKYQE-LURJTMIESA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50180254   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180254(1-((S)-2-aminopropyl)-7-iodo-1H-indazol-6-ol | CHE...)
Affinity DataKi:  4.80nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180254(1-((S)-2-aminopropyl)-7-iodo-1H-indazol-6-ol | CHE...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180254(1-((S)-2-aminopropyl)-7-iodo-1H-indazol-6-ol | CHE...)
Affinity DataKi:  21nMAssay Description:Displacement of [125I]DOI from cloned human 5HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180254(1-((S)-2-aminopropyl)-7-iodo-1H-indazol-6-ol | CHE...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of [125I]DOI binding to 5HT2A receptor in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Alcon Research

Curated by ChEMBL
LigandPNGBDBM50180254(1-((S)-2-aminopropyl)-7-iodo-1H-indazol-6-ol | CHE...)
Affinity DataEC50:  204nMAssay Description:Activity against 5HT2A mediated intracellular calcium mobilization by FLIPR in rat vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed