BDBM50180460 3,8-dihydroxy-4,7-dimethyl-6H-benzo[c]chromen-6-one::CHEMBL204922

SMILES Cc1c(O)ccc2c1oc(=O)c1c(C)c(O)ccc21

InChI Key InChIKey=JLALBSSBYZKONR-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50180460   

TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180460(3,8-dihydroxy-4,7-dimethyl-6H-benzo[c]chromen-6-on...)
Affinity DataIC50: 4.10nMAssay Description:Binding affinity to ERbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180460(3,8-dihydroxy-4,7-dimethyl-6H-benzo[c]chromen-6-on...)
Affinity DataEC50:  7.20nMAssay Description:Binding affinity to ERbeta in HTRF coactivator recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180460(3,8-dihydroxy-4,7-dimethyl-6H-benzo[c]chromen-6-on...)
Affinity DataIC50: 78nMAssay Description:Binding affinity to ERbeta in presence of serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50180460(3,8-dihydroxy-4,7-dimethyl-6H-benzo[c]chromen-6-on...)
Affinity DataIC50: 159nMAssay Description:Binding affinity to ERalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed