BDBM50182559 1-(3,4-dihydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1-one::CHEMBL202846

SMILES CCCC(N1CCCC1)C(=O)c1ccc(O)c(O)c1

InChI Key InChIKey=KKTUFJIEHNEGDF-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50182559   

LigandPNGBDBM50182559(1-(3,4-dihydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182559(1-(3,4-dihydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1...)
Affinity DataIC50: 42nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182559(1-(3,4-dihydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1...)
Affinity DataKi:  84nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182559(1-(3,4-dihydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1...)
Affinity DataKi:  219nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182559(1-(3,4-dihydroxyphenyl)-2-pyrrolidin-1-yl-pentan-1...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed