BDBM50182566 1-(3,4-dimethoxyphenyl)-2-pyrrolidin-1-yl-pentan-1-one::CHEMBL382768

SMILES CCCC(N1CCCC1)C(=O)c1ccc(OC)c(OC)c1

InChI Key InChIKey=AGRVUDWDZKZCAA-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50182566   

TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182566(1-(3,4-dimethoxyphenyl)-2-pyrrolidin-1-yl-pentan-1...)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of [3H] serotonin uptake into human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182566(1-(3,4-dimethoxyphenyl)-2-pyrrolidin-1-yl-pentan-1...)
Affinity DataKi:  7.46E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182566(1-(3,4-dimethoxyphenyl)-2-pyrrolidin-1-yl-pentan-1...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182566(1-(3,4-dimethoxyphenyl)-2-pyrrolidin-1-yl-pentan-1...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed