BDBM50182567 1-(4-hydroxymethylphenyl)-2-pyrrolidin-1-yl-pentan-1-one::CHEMBL203562

SMILES CCCC(N1CCCC1)C(=O)c1ccc(CO)cc1

InChI Key InChIKey=FDCLNKXJEZCPEW-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50182567   

TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182567(1-(4-hydroxymethylphenyl)-2-pyrrolidin-1-yl-pentan...)
Affinity DataIC50: 44.3nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182567(1-(4-hydroxymethylphenyl)-2-pyrrolidin-1-yl-pentan...)
Affinity DataIC50: 12.4nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182567(1-(4-hydroxymethylphenyl)-2-pyrrolidin-1-yl-pentan...)
Affinity DataKi:  48.7nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182567(1-(4-hydroxymethylphenyl)-2-pyrrolidin-1-yl-pentan...)
Affinity DataKi:  150nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182567(1-(4-hydroxymethylphenyl)-2-pyrrolidin-1-yl-pentan...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed