BDBM50182570 1-(3-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one::CHEMBL426304

SMILES CCCC(N1CCCC1)C(=O)c1cccc(I)c1

InChI Key InChIKey=NYDUTEZMPZHSRY-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50182570   

TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182570(1-(3-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of [3H] serotonin uptake into human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182570(1-(3-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataIC50: 52nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182570(1-(3-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataIC50: 81nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182570(1-(3-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataKi:  109nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182570(1-(3-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataKi:  670nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182570(1-(3-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed