BDBM50182577 1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one::CHEMBL202479

SMILES CCCC(N1CCCC1)C(=O)c1ccc(I)cc1

InChI Key InChIKey=QXBWECFEEZMKTN-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50182577   

TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182577(1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataIC50: 32nMAssay Description:Inhibition of [3H] dopamine uptake into human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182577(1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataIC50: 46.5nMAssay Description:Inhibition of [3H] norepinephrine uptake into human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182577(1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataIC50: 197nMAssay Description:Inhibition of [3H] serotonin uptake into human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182577(1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataKi:  81.4nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Organix

Curated by ChEMBL
LigandPNGBDBM50182577(1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataKi:  301nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed
LigandPNGBDBM50182577(1-(4-iodophenyl)-2-pyrrolidin-1-yl-pentan-1-one | ...)
Affinity DataKi:  310nMAssay Description:Displacement of [125I]RTI-55 from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2012
Entry Details Article
PubMed