BDBM50183073 CHEMBL3818805

SMILES Clc1ccc2n(C3CCN(CCCCc4c[nH]c5ccccc45)CC3)c(=O)[nH]c2c1

InChI Key InChIKey=ADUYXHYSTCIMEO-UHFFFAOYSA-N

Data  14 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50183073   

TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50183073(CHEMBL3818805)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]N-methylspiperone from human recombinant dopamine D4 receptor incubated for 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50183073(CHEMBL3818805)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]N-methylspiperone from human recombinant dopamine D4 receptor incubated for 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50183073(CHEMBL3818805)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]Citalopram from human recombinant SERT incubated for 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50183073(CHEMBL3818805)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]Citalopram from human recombinant SERT incubated for 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50183073(CHEMBL3818805)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]N-methylspiperone from human recombinant dopamine D3 receptor incubated for 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50183073(CHEMBL3818805)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT2B receptor incubated for 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50183073(CHEMBL3818805)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT2B receptor incubated for 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50183073(CHEMBL3818805)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]N-methylspiperone from human recombinant dopamine D3 receptor incubated for 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50183073(CHEMBL3818805)
Affinity DataKi:  111nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor incubated for 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50183073(CHEMBL3818805)
Affinity DataKi:  112nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor incubated for 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50183073(CHEMBL3818805)
Affinity DataKi:  134nMAssay Description:Displacement of [3H]N-methylspiperone from human recombinant dopamine D2 receptor incubated for 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50183073(CHEMBL3818805)
Affinity DataKi:  135nMAssay Description:Displacement of [3H]N-methylspiperone from human recombinant dopamine D2 receptor incubated for 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50183073(CHEMBL3818805)
Affinity DataKi:  245nMAssay Description:Displacement of [3H]Pyrilamine from human recombinant histamine H1 receptor incubated for 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50183073(CHEMBL3818805)
Affinity DataKi:  255nMAssay Description:Displacement of [3H]Pyrilamine from human recombinant histamine H1 receptor incubated for 1.5 hrs by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2017
Entry Details Article
PubMed