BDBM50183534 (R)-(-)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fluorophenyl)methoxy]ethyl]piperidine dioxalate::CHEMBL204814

SMILES N[C@@H](CN1CCC(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1)Cc1ccccc1

InChI Key InChIKey=YGBCDXIPWNLLEI-MUUNZHRXSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50183534   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183534((R)-(-)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I]RTI-55 from DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183534((R)-(-)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)
Affinity DataKi:  17nMAssay Description:Inhibition of [3H]DA uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183534((R)-(-)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)
Affinity DataKi:  68nMAssay Description:Displacement of [125I]RTI-55 from SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183534((R)-(-)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)
Affinity DataKi:  229nMAssay Description:Inhibition of [3H]5HT uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183534((R)-(-)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)
Affinity DataKi:  402nMAssay Description:Inhibition of [3H]NE uptakeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Niddk

Curated by ChEMBL
LigandPNGBDBM50183534((R)-(-)-1-(2-amino-3-phenylpropyl)-4-[2-[bis-(4-fl...)
Affinity DataKi:  941nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed