BDBM50183806 4-(methylsulfonyl)-N-(3-(6-(2-(methylsulfonyl)propan-2-yl)quinolin-8-yl)phenyl)benzamide::CHEMBL208236
SMILES CC(C)(c1cc(-c2cccc(NC(=O)c3ccc(cc3)S(C)(=O)=O)c2)c2ncccc2c1)S(C)(=O)=O
InChI Key InChIKey=HGDWTVWVCTUICT-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50183806
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human GST-PDE4DMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human GST-PDE4AMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human GST-PDE4BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to block TNFalpha release through inhibition of PDE4 in LPS-stimulated human whole bloodMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Merck Frosst Center For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 10.6nMAssay Description:Inhibition of human GST-PDE4CMore data for this Ligand-Target Pair