BDBM50185970 CHEMBL207301::methyl 4-({1-[3-((3,4-Dichlorophenyl){[1-(methylsulfonyl)-piperidin-4-yl]carbonyl}amino)propyl]piperidin-4-yl}methyl)-benzoate

SMILES COC(=O)c1ccc(CC2CCN(CCCN(C(=O)C3CCN(CC3)S(C)(=O)=O)c3ccc(Cl)c(Cl)c3)CC2)cc1

InChI Key InChIKey=XJXVLMRPZYJMPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185970   

TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185970(CHEMBL207301 | methyl 4-({1-[3-((3,4-Dichloropheny...)
Affinity DataIC50:  7nMAssay Description:Inhibition of membrane fusion between HIV1 JR-FL Env-expressing COS7 cells and MOLT4/CCR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50185970(CHEMBL207301 | methyl 4-({1-[3-((3,4-Dichloropheny...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of [125I]RANTES binding to human CCR5 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed