BDBM50187218 (S)-1-(3,4,5-trichloro-2-hydroxyphenylsulfonyl)pyrrolidine-2-carboxylic acid::CHEMBL210597

SMILES OC(=O)[C@@H]1CCCN1S(=O)(=O)c1cc(Cl)c(Cl)c(Cl)c1O

InChI Key InChIKey=SMIZKRHOEQTUGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50187218   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187218((S)-1-(3,4,5-trichloro-2-hydroxyphenylsulfonyl)pyr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Cytotoxicity against human Huh7 cell line containing HCV genotype 1b repliconMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50187218((S)-1-(3,4,5-trichloro-2-hydroxyphenylsulfonyl)pyr...)
Affinity DataIC50: 80nMAssay Description:Cytotoxicity against human Huh7 cell line containing HCV genotype 1b repliconMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed