BDBM50187824 CHEMBL210154::methyl 3-(4-cyano-3-hydroxyisothiazol-5-ylamino)benzoate

SMILES COC(=O)c1cccc(Nc2s[nH]c(=O)c2C#N)c1

InChI Key InChIKey=COROHTXLUARPRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50187824   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Valeant Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50187824(methyl 3-(4-cyano-3-hydroxyisothiazol-5-ylamino)be...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed