BDBM50188379 4-(4-fluorophenyl)-8-[2-(3-fluorophenyl)-2-hydroxycyclohexyl]-7-methyl-2,8-diazaspiro[4.5]decan-1-one::CHEMBL386805

SMILES CC1CC2(CCN1C1CCCCC1(O)c1cccc(F)c1)C(CNC2=O)c1ccc(F)cc1

InChI Key InChIKey=FEJOUUANXZMYSD-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50188379   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188379(4-(4-fluorophenyl)-8-[2-(3-fluorophenyl)-2-hydroxy...)
Affinity DataEC50:  474nMAssay Description:Inhibition of [3H]glycine uptake at human GlyT1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed