BDBM50189549 CHEMBL3827756

SMILES CCCCCCSc1nc(O)cc(O)n1

InChI Key InChIKey=UYXOAKRMLQKLQX-UHFFFAOYSA-N

Data  1 KI  13 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50189549   

TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataKi:  0.219nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  144nMAssay Description:Agonist activity at GPR84 (unknown origin) expressed in in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  213nMAssay Description:Agonist activity at recombinant human GPR84 stably expressed in HEK293 cells co-expressing Galpha16 assessed as increase in intracellular calcium mob...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  0.790nMAssay Description:Agonist activity at recombinant human N-terminal epitope tagged/C-terminal eYFP-fused FLAG-tagged GPR84 expressed in Flp-In TREx 293 cell membranes a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  1nMAssay Description:Agonist activity at recombinant human N-terminal epitope tagged/C-terminal eYFP-fused FLAG-tagged GPR84 expressed in Flp-In TREx 293 cell membranes a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Mus musculus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  13nMAssay Description:Agonist activity at GPR84 in mouse bone-marrow-derived neutrophils assessed as stimulation of [35S]GTPgammaS binding incubated for 60 mins by liquid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  597nMAssay Description:Agonist activity at recombinant human GPR84 expressed in HEK293 cells assessed as beta-arrestin 2 recruitment measured after 20 mins by luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  8.13E+3nMAssay Description:Agonist activity at human GPR84 expressed in CHO-K1 cells assessed as induction of beta-arrestin recruitment by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human Galphai2-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as stimulation of [35S]GTPgammaS binding ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Mus musculus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  30nMAssay Description:Agonist activity at mouse Galphai2-coupled GPR84 expressed in human Flp-In-T-REx-293 cell membrane assessed as stimulation of [35S]GTPgammaS binding ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  16nMAssay Description:Agonist activity at GPR84 in LPS-treated human THP-1 cell membrane assessed as stimulation of [35S]GTPgammaS binding incubated for 60 mins by liquid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Mus musculus)
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  26nMAssay Description:Agonist activity at GPR84 in LPS-treated mouse RAW 264.7 cell membrane assessed as stimulation of [35S]GTPgammaS binding incubated for 60 mins by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  139nMAssay Description:Agonist activity at GPR84 (unknown origin) expressed in HEK293 cells coexpressing Galpha16 protein by Fluo-4 AM dye based calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled receptor 84(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50189549(CHEMBL3827756)
Affinity DataEC50:  134nMAssay Description:Agonist activity at recombinant human GPR84 stably expressed in HEK293 cells co-expressing Galpha16 assessed as inhibition of forskolin-induced cAMP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed