BDBM50189749 5-(5-benzo[1,3]dioxol-5-yl-furan-2-ylmethylene)thiazolidine-2,4-dione::CHEMBL209193

SMILES OC1=NC(=O)C(S1)=Cc1ccc(o1)-c1ccc2OCOc2c1

InChI Key InChIKey=OBARDFKYNXOLOA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50189749   

LigandPNGBDBM50189749(5-(5-benzo[1,3]dioxol-5-yl-furan-2-ylmethylene)thi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin) assessed as decrease in fluorescence intensity using phosphorylated substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
LigandPNGBDBM50189749(5-(5-benzo[1,3]dioxol-5-yl-furan-2-ylmethylene)thi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Serono Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50189749(5-(5-benzo[1,3]dioxol-5-yl-furan-2-ylmethylene)thi...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed