BDBM501912 US11028075, Example 45
SMILES CN(C1CN(C)C1)[C@H]1C[C@H](CC[C@@H]1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ccncn1)c1cccc(c1)C(F)(F)F
InChI Key InChIKey=JTBLHIRZHKGGLA-WYRQLCSISA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 501912
Affinity DataIC50: 0.241nMAssay Description:The following voltage clamp electrophysiology studies are performed on representative compounds using cells heterologously expressing Nav1.7 or Nav1....More data for this Ligand-Target Pair
Affinity DataIC50: 0.399nMAssay Description:Saturation experiments. A competitive NaV1.7 inhibitor having a methyl group is tritiated. Three tritiums are incorporated in place of methyl hydroge...More data for this Ligand-Target Pair