BDBM50192144 2-(3-chloro-4-(ethyl(phenethyl)amino)phenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol::CHEMBL386530

SMILES CCN(CCc1ccccc1)c1ccc(cc1Cl)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=IUJVGMXTNWYJCB-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50192144   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192144(2-(3-chloro-4-(ethyl(phenethyl)amino)phenyl)-1,1,1...)
Affinity DataEC50:  90nMAssay Description:Transactivation of LXRbeta by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192144(2-(3-chloro-4-(ethyl(phenethyl)amino)phenyl)-1,1,1...)
Affinity DataIC50:  6nMAssay Description:Binding affinity to LXRalpha by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192144(2-(3-chloro-4-(ethyl(phenethyl)amino)phenyl)-1,1,1...)
Affinity DataEC50:  800nMAssay Description:Transactivation of LXRalpha by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50192144(2-(3-chloro-4-(ethyl(phenethyl)amino)phenyl)-1,1,1...)
Affinity DataIC50:  3nMAssay Description:Binding affinity to LXRbeta by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed