BDBM501926 US11028075, Example 59
SMILES CN(C)[C@H]1C[C@H](CC[C@@H]1Oc1cc(F)c(cc1F)S(=O)(=O)Nc1ccncn1)c1cccc(OC(F)(F)F)c1
InChI Key InChIKey=BZRJLKIQFCVVGF-NDXORKPFSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 501926
Affinity DataIC50: 1.62nMAssay Description:The following voltage clamp electrophysiology studies are performed on representative compounds using cells heterologously expressing Nav1.7 or Nav1....More data for this Ligand-Target Pair
Affinity DataIC50: 32.6nMAssay Description:Saturation experiments. A competitive NaV1.7 inhibitor having a methyl group is tritiated. Three tritiums are incorporated in place of methyl hydroge...More data for this Ligand-Target Pair