BDBM50192858 CHEMBL3358966

SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12

InChI Key InChIKey=CGXHFSJDSWAEMT-UHFFFAOYSA-N

Data  25 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50192858   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50:  500nMAssay Description:Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant ARK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant Aurora B using Tetra(LRRWSLG) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant COTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CDK2/cyclin A using histone H1 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant ERBB2 using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human recombinant VEGFR3 using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant IGF1R using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant EPHB4 using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant PLK1 using Casein substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of human recombinant FLT3 using poly(Ala,Glu,Lys,Tyr) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant INSR using poly(Ala,Glu,Lys,Tyr) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant AKT1 using GSK3/14-27 substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant Aurora A using Tetra(LRRWSLG) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant B-RAF-VE using MEK1 KM substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CK2A1 using Casein substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant SAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant EGFR using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50:  900nMAssay Description:Inhibition of human c-KiTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human recombinant VEGFR2 using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant CDK4/Cyclin D1 using b-CTF substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant FAK using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MET using poly(Ala,Glu,Lys,Tyr) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant SRC using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Christian-Albrechts-University Of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant TIE2 using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed