BDBM50192904 10R-hydroxylobelane::CHEMBL213148

SMILES CN1[C@@H](CCc2ccccc2)CCC[C@H]1C[C@@H](O)c1ccccc1

InChI Key InChIKey=MUSFCRGEWKAWEE-BHIFYINESA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50192904   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192904(10R-hydroxylobelane | CHEMBL213148)
Affinity DataKi:  570nMAssay Description:Inhibition of [3H]DA uptake at DAT in rat striatal synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSynaptic vesicular amine transporter(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192904(10R-hydroxylobelane | CHEMBL213148)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192904(10R-hydroxylobelane | CHEMBL213148)
Affinity DataKi:  7.30E+3nMAssay Description:Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192904(10R-hydroxylobelane | CHEMBL213148)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of [3H]NIC binding to alpha4beta2 nAChR in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50192904(10R-hydroxylobelane | CHEMBL213148)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of [3H]MLA binding to alpha7 nAChR in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed