BDBM107898 CHEMBL373487::US8604218, 1.049

SMILES Cc1n[nH]c2ccc(NC3CCCN(Cc4ccccc4)C3)cc12

InChI Key InChIKey=RWIWATQFHWUZHC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107898   

TargetRho-associated protein kinase 2(Human)
Inspire Pharmaceuticals

US Patent
LigandPNGBDBM107898(CHEMBL373487 | US8604218, 1.049)
Affinity DataIC50: 604nMpH: 7.2Assay Description:Inhibition of ROCK2 activity was determined using the IMAP Screening Express Kit (Molecular Devices product number #8073). ROCK2 kinase (UpstateChemi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2014
Entry Details
US Patent

TargetRho-associated protein kinase 1/2(Human)
Kirin Brewery

Curated by ChEMBL
LigandPNGBDBM107898(CHEMBL373487 | US8604218, 1.049)
Affinity DataIC50: 150nMAssay Description:Inhibition of Rho kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed