BDBM50198032 CHEMBL227553::[(R)-2-methyl-1-(4-phenethyl-benzenesulfonylamino)-propyl]-phosphonic acid

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(CCc2ccccc2)cc1)P(O)(O)=O

InChI Key InChIKey=FHZGYMLWCVBBPM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50198032   

TargetMatrix metalloproteinase-9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198032([(R)-2-methyl-1-(4-phenethyl-benzenesulfonylamino)...)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human recombinant MMP9 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198032([(R)-2-methyl-1-(4-phenethyl-benzenesulfonylamino)...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198032([(R)-2-methyl-1-(4-phenethyl-benzenesulfonylamino)...)
Affinity DataIC50: 260nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198032([(R)-2-methyl-1-(4-phenethyl-benzenesulfonylamino)...)
Affinity DataIC50: 820nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198032([(R)-2-methyl-1-(4-phenethyl-benzenesulfonylamino)...)
Affinity DataIC50: 980nMAssay Description:Inhibition of human recombinant MMP2 expressed in mouse myeloma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrilysin(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50198032([(R)-2-methyl-1-(4-phenethyl-benzenesulfonylamino)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed