BDBM50199636 1-(3-(4-fluorobenzyloxy)phenyl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine::CHEMBL394998

SMILES Nc1nccn2c(nc(-c3cccc(OCc4ccc(F)cc4)c3)c12)C1CCC1

InChI Key InChIKey=JZDVBZKWDYAEIW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199636   

TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199636(1-(3-(4-fluorobenzyloxy)phenyl)-3-cyclobutylimidaz...)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of human recombinant GST-IGF1R activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed