BDBM50199653 1-(3-(2-(difluoromethoxy)benzyloxy)phenyl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine::CHEMBL399192

SMILES Nc1nccn2c(nc(-c3cccc(OCc4ccccc4OC(F)F)c3)c12)C1CCC1

InChI Key InChIKey=SYXCOPRMXTYKNO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50199653   

TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50199653(1-(3-(2-(difluoromethoxy)benzyloxy)phenyl)-3-cyclo...)
Affinity DataIC50: 3.28E+3nMAssay Description:Inhibition of human recombinant GST-IGF1R activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed