BDBM50208447 CHEMBL3883955
SMILES Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(=O)n(n2)-c2c(F)cccc2F)CC1
InChI Key InChIKey=JCSJNNBJTFWLCL-UHFFFAOYSA-N
Data 14 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50208447
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Displacement of [3H] ketanserin from 5-HT2A receptor in Sprague-Dawley rat cerebral cortex incubated for 30 mins by liquid scintillation counting ana...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Binding affinity to 5-HT6 receptor (unknown origin)More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in Sprague-Dawley rat striatum incubated for 30 mins by liquid scintillation counting analysi...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]lysergic acid diethylamide from human recombinant 5-HT6 receptor expressed in CHO cell membranes for 30 mins by liquid scintillat...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley rat cerebral cortex incubated for 30 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens)
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 36nMAssay Description:Binding affinity to dopamine D3 receptor (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 337nMAssay Description:Binding affinity to alpha1 adrenoceptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 1.58E+3nMAssay Description:Binding affinity to 5-HT2C receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 1.58E+3nMAssay Description:Displacement of [3H]mesulergine from 5-HT2C receptor in Sprague-Dawley rat cerebral cortex incubated for 15 mins in presence of spiperone by liquid s...More data for this Ligand-Target Pair
TargetHistamine H1 receptor(Homo sapiens (Human))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Binding affinity to histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
Huazhong University Of Science And Technology
Curated by ChEMBL
Huazhong University Of Science And Technology
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum incubated for 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair