BDBM50210381 CHEMBL228736::methyl 2-(4-hydroxy-4-phenylpiperidin-1-yl)-2-phenylacetate

SMILES COC(=O)C(N1CCC(O)(CC1)c1ccccc1)c1ccccc1

InChI Key InChIKey=QESUWOVHACTYFJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210381   

TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210381(CHEMBL228736 | methyl 2-(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  1.89E+3nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210381(CHEMBL228736 | methyl 2-(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  6.75E+3nMAssay Description:Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210381(CHEMBL228736 | methyl 2-(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  5.98E+4nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210381(CHEMBL228736 | methyl 2-(4-hydroxy-4-phenylpiperid...)
Affinity DataKi:  1.22E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed