BDBM50210413 4-phenyl-1-(phenyl(4-(trifluoromethyl)phenyl)methyl)piperidin-4-ol::CHEMBL228795

SMILES OC1(CCN(CC1)C(c1ccccc1)c1ccc(cc1)C(F)(F)F)c1ccccc1

InChI Key InChIKey=GTMJMDBNWVOYOR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210413   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210413(4-phenyl-1-(phenyl(4-(trifluoromethyl)phenyl)methy...)
Affinity DataKi:  225nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210413(4-phenyl-1-(phenyl(4-(trifluoromethyl)phenyl)methy...)
Affinity DataKi:  1.21E+3nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210413(4-phenyl-1-(phenyl(4-(trifluoromethyl)phenyl)methy...)
Affinity DataKi:  4.29E+3nMAssay Description:Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210413(4-phenyl-1-(phenyl(4-(trifluoromethyl)phenyl)methy...)
Affinity DataKi:  1.01E+4nMAssay Description:Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed